Vayne

Hold just outside Charm angle and use Tumble sideways, not forward, until Charm is down. Once she misses it or burns a Spirit Rush charge defensively, turn on Final Hour and stay close enough to keep Silver Bolts cycling through her dashes.

Later Finished Vayne is stronger in a side-lane all-in if Charm is dodged, but Ahri still offers safer pick threat in teamfights. Do not front-line into fog; enter fights after Charm is shown and use Final Hour invisibility to make her Spirit Rush targeting awkward.

• •Tumble perpendicular to Orb so you avoid both the outgoing magic damage and the return true damage.
• •Condemn is best after her first Spirit Rush dash, when she has committed a direction.
• •Do not chase in a straight line through minions; Charm becomes easier for her to line up.
• •If she uses Spirit Rush only to kite, count charges before committing Flash or Condemn.

BuyQuicksilver Sash1,550g (830g to combine)Magic Resist45Active: 90s Removes all debuffs.RecipeHexdrinker1,350g (550g to combine)Attack Damage25Magic Resist25Lifeline: Upon taking magic damage that would reduce Health below 30%, grants a Shield that absorbs 250 magic damage for 5 seconds (90 second cooldown).RecipeMercury's Treads1,200g (475g to combine)Magic Resist25Enhanced Movement: 45 Move SpeedTenacity: Reduces the duration of Stuns, Slows, Taunts, Fears, Silences, Blinds, and Immobilizes by 35%.Recipe

Keep maximum auto range before she has Shadow Dance stacks and punish every last-hit with an auto-Q-auto trade. When she enters shroud, back out of its edge instead of standing inside it; commit with Final Hour only when she has used a dash and must leave the shroud to finish you.

Later In a side lane, Vayne wins if she can keep vision and terrain for Condemn, while Akali wins messy fog fights. In teamfights, wait for Akali to spend Shadow Dance onto someone else, then reveal your position with damage only when you can immediately peel with Condemn.

• •Do not Condemn her into shroud unless it pins to a wall; otherwise you lose follow-up autos.
• •Save Tumble for the dash arrival, not the Q mark, so she cannot instantly proc it for free.
• •If she has multiple Shadow Dance charges, one knockback is not enough; kite toward a wall or teammate path.
• •Final Hour invisibility can waste one of her target reacquisition windows after she dashes.

BuyHexdrinker1,350g (550g to combine)Attack Damage25Magic Resist25Lifeline: Upon taking magic damage that would reduce Health below 30%, grants a Shield that absorbs 250 magic damage for 5 seconds (90 second cooldown).RecipeQuicksilver Sash1,550g (830g to combine)Magic Resist45Active: 90s Removes all debuffs.RecipeWit's End2,150g (850g to combine)Attack Speed40%Magic Resist25Feedback Loop: Basic Attacks deal 42 bonus magic damage On-Hit and increase your Magic Resist by 5 for 5 seconds (stacks up to 4 times.)Recipe

Stay at max range and never Tumble into Headbutt range unless Pulverize has already been used. Condemn him away after Headbutt or as he walks in, then stop hitting during Unbreakable Will unless you can safely maintain Silver Bolts without being displaced.

Later Vayne wins the side lane by kiting him, but Alistar is far more valuable as a teamfight disruptor. Save Condemn for his engage path or for the carry he is enabling, not for damage into his ultimate.

• •Condemn after Headbutt can prevent the Pulverize follow-up if you are not already in melee range.
• •Do not chase through narrow jungle paths; Pulverize becomes unavoidable there.
• •Silver Bolts is your real damage into his tank stats, but Unbreakable Will sharply delays the kill.
• •If he uses ultimate to cleanse Condemn's knockback timing, reset instead of forcing.

BuyQuicksilver Sash1,550g (830g to combine)Magic Resist45Active: 90s Removes all debuffs.Recipe

Fight at 550 range with minions or angles between you and Bandage Toss, then Tumble sideways when he casts it. If he misses Q, you can commit with Final Hour and kite backward; save Condemn for after he closes, not as poke.

Later Vayne wins side lane if she has room and Bandage Toss is missed, while Amumu is much stronger in grouped fights because Curse can lock multiple targets. In teamfights, stay split from your frontline and attack whoever is safe until Curse is spent.

• •Do not stand close enough for Curse unless Bandage Toss is already down or you can instantly Condemn.
• •Tumble directly backward is often still hit by Bandage Toss; move laterally.
• •His Tantrum reduces physical poke, so do not judge the all-in by early autos alone.
• •Final Hour movement speed helps chase after missed Q, but only if you are moving toward him.

BuyQuicksilver Sash1,550g (830g to combine)Magic Resist45Active: 90s Removes all debuffs.RecipeMercury's Treads1,200g (475g to combine)Magic Resist25Enhanced Movement: 45 Move SpeedTenacity: Reduces the duration of Stuns, Slows, Taunts, Fears, Silences, Blinds, and Immobilizes by 35%.RecipeHexdrinker1,350g (550g to combine)Attack Damage25Magic Resist25Lifeline: Upon taking magic damage that would reduce Health below 30%, grants a Shield that absorbs 250 magic damage for 5 seconds (90 second cooldown).Recipe

Stay outside Flash Frost's center line and use Tumble only after the projectile is committed, because she can punish predictable tumbles with wall. Commit only when Flash Frost is down and you have enough space to chase past egg; otherwise take short autos and back out before Glacial Storm controls the ground.

Later Vayne can eventually win a long side-lane duel if she dodges Q and has room to finish the egg, but Anivia's teamfight zone control is much stronger. Let her spend wall or stun on your frontline before entering Final Hour range.

• •Do not Condemn her away if Rebirth is available and you cannot reach the egg afterward.
• •Crystallize can ruin your Condemn angle by changing the wall geometry; wait for the wall if possible.
• •Tumble out of Glacial Storm first, then decide whether to re-enter.
• •Her 600 range means you cannot trade autos for free before she commits a spell.

BuyBanshee's Veil2,750g (875g to combine)Health450Magic Resist55Intangibility: Grants a Spell Shield that blocks the next enemy ability. This Shield refreshes after no damage is taken from enemy champions for 25 seconds.Shadow Mending: Grants 9 Health Regen per 5 for up to 10 seconds after taking damage from an enemy champion or when the Spell Shield breaks.RecipeHexdrinker1,350g (550g to combine)Attack Damage25Magic Resist25Lifeline: Upon taking magic damage that would reduce Health below 30%, grants a Shield that absorbs 250 magic damage for 5 seconds (90 second cooldown).RecipeMercury's Treads1,200g (475g to combine)Magic Resist25Enhanced Movement: 45 Move SpeedTenacity: Reduces the duration of Stuns, Slows, Taunts, Fears, Silences, Blinds, and Immobilizes by 35%.Recipe

Track her stun counter and refuse the duel when Pyromania is ready unless you can Condemn her away before she casts. If she spends stun on a spell that misses or on minions, immediately use Final Hour and fight from max auto range before Tibbers and Disintegrate cycle again.

Later Vayne wins extended side-lane fights only when Annie's stun is down; otherwise Annie's burst remains decisive. In teamfights, never be the first target in Tibbers range, and buy enough magic defense or cleanse access to survive the stun window.

• •Annie's 625 attack range lets her threaten stun setup before you can auto her.
• •Do not Tumble forward into a charged stun; invisibility does not help if she can point-click as you reappear.
• •Condemn is strongest when it denies her follow-up after Tibbers, not when used early for damage.
• •If Molten Shield is active, avoid wasting a low-value poke trade into extra resistances and return damage.

BuyQuicksilver Sash1,550g (830g to combine)Magic Resist45Active: 90s Removes all debuffs.RecipeHexdrinker1,350g (550g to combine)Attack Damage25Magic Resist25Lifeline: Upon taking magic damage that would reduce Health below 30%, grants a Shield that absorbs 250 magic damage for 5 seconds (90 second cooldown).RecipeBanshee's Veil2,750g (875g to combine)Health450Magic Resist55Intangibility: Grants a Spell Shield that blocks the next enemy ability. This Shield refreshes after no damage is taken from enemy champions for 25 seconds.Shadow Mending: Grants 9 Health Regen per 5 for up to 10 seconds after taking damage from an enemy champion or when the Spell Shield breaks.Recipe

Do not walk straight at her through Frost Shot; use brush, minions, or Final Hour movement speed to enter auto range. If Arrow is down or missed, Tumble aggressively enough to keep Silver Bolts stacking, and save Condemn for when she tries to kite backward rather than opening with it.

Later Vayne wins the side lane if she reaches Ashe without eating Arrow at long range, while Ashe brings more reliable engage and peel in teamfights. Stay off predictable flank lines and join after Arrow is used or blocked.

• •Her 600 range means the first auto is usually hers; do not bleed health before the all-in.
• •Tumble sideways through Volley gaps instead of backing away while slowed.
• •Condemn can interrupt her chase pattern by knocking her out of Frost Shot chain range.
• •Boots of Swiftness specifically reduce the pain of Frost Shot kiting.

BuyBoots of Swiftness1,000g (675g to combine)Enhanced Movement: 60 Move SpeedSlow Resist: Movement slowing effects are reduced by 25%.RecipeNinja Tabi1,000g (375g to combine)Armor25Ninja Footwork: Blocks 10% of the damage from Basic Attacks.Enhanced Movement: 45 Move SpeedRecipeQuicksilver Sash1,550g (830g to combine)Magic Resist45Active: 90s Removes all debuffs.Recipe

Stand behind minions and treat open lanes as danger until Rocket Grab is used. Once he misses, step forward with Final Hour or normal autos, Condemn his Overdrive approach, and keep enough distance that Power Fist never connects.

Later Vayne wins isolated side-lane fights cleanly if Grab is dodged, but Blitzcrank can decide teamfights with one pick. Do not show first around objectives; make him hook someone else or spend Q before you enter damage range.

• •Tumble sideways when his arm starts, not backward along the hook line.
• •Condemn after Overdrive starts wastes his best way to reach Power Fist range.
• •Mana Barrier makes his last 20% health deceptive; keep kiting until it expires or you can finish through it.
• •Do not chase around blind corners where Rocket Grab has no minion blockers.

BuyQuicksilver Sash1,550g (830g to combine)Magic Resist45Active: 90s Removes all debuffs.RecipeNinja Tabi1,000g (375g to combine)Armor25Ninja Footwork: Blocks 10% of the damage from Basic Attacks.Enhanced Movement: 45 Move SpeedRecipe

Keep minions between you and Sear when Blaze is on you, and Tumble out of Pillar of Flame's delay instead of using Q for damage greed. Commit only after Sear misses or Brand has used Conflagration without creating a stun threat; then stay close enough to finish before cooldowns return.

Later Vayne can win side lane if she dodges Sear, but Brand is more dangerous in grouped fights because Pyroclasm punishes clustered allies. Approach from an angle, avoid standing near teammates or minions during his ultimate, and use Final Hour to break his targeting rhythm.

• •If Blaze is active on you, every Sear angle becomes lethal; reset your pathing first.
• •Do not fight him inside your own minion wave when Pyroclasm is available.
• •Condemn can stop his follow-up spacing, but it does not save you if Sear has already stunned you.
• •Hexdrinker is strongest before his full combo starts one-shotting.

BuyHexdrinker1,350g (550g to combine)Attack Damage25Magic Resist25Lifeline: Upon taking magic damage that would reduce Health below 30%, grants a Shield that absorbs 250 magic damage for 5 seconds (90 second cooldown).RecipeQuicksilver Sash1,550g (830g to combine)Magic Resist45Active: 90s Removes all debuffs.RecipeBanshee's Veil2,750g (875g to combine)Health450Magic Resist55Intangibility: Grants a Spell Shield that blocks the next enemy ability. This Shield refreshes after no damage is taken from enemy champions for 25 seconds.Shadow Mending: Grants 9 Health Regen per 5 for up to 10 seconds after taking damage from an enemy champion or when the Spell Shield breaks.Recipe

Hold max range and keep moving diagonally so Rupture has to predict, not react. If Rupture misses, fight forward with autos and save Condemn for after he walks into silence range; never Tumble aggressively while Feral Scream can prevent your next escape.

Later Vayne becomes one of the best side-lane answers to Cho'Gath once her attack speed and damage are finished. In teamfights, respect his silence and Feast range, and hit him only when he is the closest safe target rather than tunneling past him.

• •Silver Bolts ignores his large health pool, so extended uptime matters more than burst items.
• •Do not stand near terrain unless you are ready to Condemn him into it; his model can body-block your escape.
• •Feral Scream can stop both Tumble timing and Condemn peel, so bait it with spacing first.
• •If Feast can execute you, lifesteal trades are less reliable than staying out of range.

BuyQuicksilver Sash1,550g (830g to combine)Magic Resist45Active: 90s Removes all debuffs.RecipeMercury's Treads1,200g (475g to combine)Magic Resist25Enhanced Movement: 45 Move SpeedTenacity: Reduces the duration of Stuns, Slows, Taunts, Fears, Silences, Blinds, and Immobilizes by 35%.RecipeBoots of Swiftness1,000g (675g to combine)Enhanced Movement: 60 Move SpeedSlow Resist: Movement slowing effects are reduced by 25%.Recipe

Trade in short angles where Phosphorus Bomb and Missile Barrage do not both land, then back out before Gatling Gun gets full value. Commit after Valkyrie is used or forced defensively; Condemn him out of Gatling Gun's cone or into terrain when he turns to fight.

Later Vayne is the better pure side-lane duelist if she can force Corki to spend Valkyrie, while Corki contributes safer poke before teamfights. Do not lose half health to missiles before the fight; enter after his poke pattern is interrupted and force short-range autos.

• •Tumble across Gatling Gun's cone rather than straight away from it.
• •If Valkyrie is up, Condemn alone usually does not secure the chase.
• •Do not stand in Valkyrie's burn trail while trying to finish Silver Bolts.
• •Corki's true-damage autos make small health leads less stable than they look.

BuyNinja Tabi1,000g (375g to combine)Armor25Ninja Footwork: Blocks 10% of the damage from Basic Attacks.Enhanced Movement: 45 Move SpeedRecipeQuicksilver Sash1,550g (830g to combine)Magic Resist45Active: 90s Removes all debuffs.Recipe

Keep max range and Tumble sideways on cleaver windups; do not kite in a straight retreat path. When Sadism starts, keep attacking if you have space and apply Grievous Wounds if available, but Condemn him away the moment a cleaver slow lets him enter melee.

Later Vayne wins the side lane very hard once she has attack speed, while Mundo is mostly a soak and disruption body in teamfights. Hit him when he is the closest target and do not overchase through cleaver angles if the enemy backline is still free-hitting.

• •Executioner's Calling is specifically valuable because Sadism is the duel extender.
• •Silver Bolts keeps scaling through his health buys, so patience beats burst racing.
• •Condemn after a landed cleaver is often better than before, because it denies the melee follow-up.
• •Boots of Swiftness can matter if cleavers are the only way he reaches you.

BuyExecutioner's Calling1,900g (700g to combine)Attack Damage25Critical Strike Chance20%Rending Strike: Basic Attacks inflict Grievous Wounds on enemy champions for 1.5 seconds On-Hit. (Grievous Wounds reduces incoming healing and regeneration effects by 50%.)RecipeBoots of Swiftness1,000g (675g to combine)Enhanced Movement: 60 Move SpeedSlow Resist: Movement slowing effects are reduced by 25%.RecipeFrozen Mallet3,300g (950g to combine)Attack Damage30Health700Icy: Basic Attacks Slow the target's Move Speed for 1.5 seconds On-Hit (40% Slow for Melee Attacks, 30% Slow for Ranged Attacks). "We brought it back just for you."Recipe

Avoid isolated fog paths and keep near walls where Condemn can punish her reveal. When she appears, Condemn immediately if she is in melee pathing range; if she uses Agony's Embrace first, Tumble out of the slow edge before turning with Final Hour.

Later Vayne can win a clean side-lane duel with vision and wall access, but Evelynn is better at finding unfair fights before teams are set. In teamfights, stay near peel and do not reveal yourself chasing until Evelynn has shown or committed ultimate.

• •Her camouflage means the matchup is often decided before health bars trade.
• •Do not save Condemn too long; Ravage range means she is already where she wants to be.
• •Final Hour invisibility can break her follow-up targeting after she reveals.
• •A ward item or defensive vision is more matchup-specific here than another damage component.

BuyQuicksilver Sash1,550g (830g to combine)Magic Resist45Active: 90s Removes all debuffs.RecipeHexdrinker1,350g (550g to combine)Attack Damage25Magic Resist25Lifeline: Upon taking magic damage that would reduce Health below 30%, grants a Shield that absorbs 250 magic damage for 5 seconds (90 second cooldown).RecipeSightstone800g (325g to combine)Health180Ward Refresh: Holds 3 charges and refills upon visiting the shop.Active: Consumes a charge to place an invisible ward that reveals the surrounding area for 3 minutes (maximum 2 wards placed from this item at once).Recipe

Stand behind minions to reduce Mystic Shot poke and do not Tumble forward until Arcane Shift is used or you can Condemn him into terrain immediately. Once Shift is down, use Final Hour to stay attached and sidestep Mystic Shot between autos rather than chasing in a straight line.

Later Vayne is stronger in a true side-lane all-in, but Ezreal is safer in teamfights and sieges because he can contribute before committing. Preserve health before objectives, then force him to Shift defensively before you spend Condemn.

• •Do not Condemn while Arcane Shift is available unless the wall angle is immediate.
• •Essence Flux's attack speed reduction can swing an auto duel; wait it out if he lands it early.
• •Minions are your best defense against Mystic Shot cooldown cycling.
• •Trueshot Barrage's channel is a free reposition cue; Tumble out of the line, then re-engage.

BuyNinja Tabi1,000g (375g to combine)Armor25Ninja Footwork: Blocks 10% of the damage from Basic Attacks.Enhanced Movement: 45 Move SpeedRecipe

Stay outside Terrify range until he spends it or you have Quicksilver Sash available. Interrupt Drain with Condemn as soon as it starts, then commit during that cooldown; if Crowstorm channels from fog, Tumble out first and fight only after the fear threat is answered.

Later Vayne can kill Fiddlesticks in side lane if she has cleanse access and interrupts Drain, but Fiddlesticks has much higher teamfight swing with Crowstorm. Keep spread, keep vision over flank channels, and save Condemn or QSS for the first crowd-control chain.

• •Condemn cancels Drain; holding it too long lets him heal through your autos.
• •Quicksilver Sash is a real damage item in this matchup because it buys auto uptime after Terrify.
• •Do not duel from brush or fog entrances where Crowstorm can start on top of you.
• •Dark Wind silence can prevent your escape after fear, so cleanse timing matters.

BuyQuicksilver Sash1,550g (830g to combine)Magic Resist45Active: 90s Removes all debuffs.RecipeMercury's Treads1,200g (475g to combine)Magic Resist25Enhanced Movement: 45 Move SpeedTenacity: Reduces the duration of Stuns, Slows, Taunts, Fears, Silences, Blinds, and Immobilizes by 35%.RecipeHexdrinker1,350g (550g to combine)Attack Damage25Magic Resist25Lifeline: Upon taking magic damage that would reduce Health below 30%, grants a Shield that absorbs 250 magic damage for 5 seconds (90 second cooldown).Recipe

Do not let him soften you with repeated Parrrley before the all-in; answer with auto-Q-auto only when you can reset safely. Commit after Remove Scurvy is used for healing or after he drops Cannon Barrage poorly, then Condemn him away when he tries to convert the slow into melee autos.

Later Vayne generally wins the side-lane duel when she has lifesteal and attack speed, while Gangplank brings global zone control and team buffs. In teamfights, leave Cannon Barrage before chasing and do not rely on Condemn's crowd control to stick him because Remove Scurvy cleanses it.

• •Remove Scurvy can erase Condemn's stun value, so use Condemn more for distance than lockdown.
• •Parrrley applies his lane pressure without entering your auto range; avoid losing the fight before it starts.
• •Boots of Swiftness helps against Cannon Barrage and passive slow patterns.
• •If Raise Morale is active, respect his movement speed before choosing an all-in angle.

BuyBoots of Swiftness1,000g (675g to combine)Enhanced Movement: 60 Move SpeedSlow Resist: Movement slowing effects are reduced by 25%.RecipeNinja Tabi1,000g (375g to combine)Armor25Ninja Footwork: Blocks 10% of the damage from Basic Attacks.Enhanced Movement: 45 Move SpeedRecipe

Hold just outside his melee range and tag him often enough to stop Perseverance. Save Condemn for Decisive Strike, not for damage; once Q is spent or he is knocked back, chase with Night Hunter and stack Silver Bolts.

Later Vayne owns the side lane unless she face-checks into silence range, while Garen is mostly a frontliner in teamfights. Hit whoever is closest and do not Tumble forward while Demacian Justice can execute you.

• •Auto him periodically so Perseverance never gets a free reset.
• •Condemn after he starts Decisive Strike, not before; Q breaks slows, not knockback.
• •If he spins away with Judgment, keep following only while Condemn is available.

BuyBoots of Swiftness1,000g (675g to combine)Enhanced Movement: 60 Move SpeedSlow Resist: Movement slowing effects are reduced by 25%.RecipeFrozen Mallet3,300g (950g to combine)Attack Damage30Health700Icy: Basic Attacks Slow the target's Move Speed for 1.5 seconds On-Hit (40% Slow for Melee Attacks, 30% Slow for Ranged Attacks). "We brought it back just for you."Recipe

Stand off-angle from Barrel Roll and keep Tumble for Body Slam rather than poke. If he misses Body Slam, you have the window to Final Hour and chase; if he still has Explosive Cask, avoid walls and do not let it throw you back into him.

Later Finished Vayne can kill him in a long side-lane fight, but Gragas is more dangerous in grouped fights because Cask can split you from peel. Buy magic protection if his combo is deciding fights, then wait out Body Slam before committing.

• •Do not auto through Barrel Roll's attack-speed slow unless you are already winning the all-in.
• •Tumble sideways from Body Slam, not straight back.
• •After Explosive Cask is down, he has far less control over your Final Hour chase.

BuyBanshee's Veil2,750g (875g to combine)Health450Magic Resist55Intangibility: Grants a Spell Shield that blocks the next enemy ability. This Shield refreshes after no damage is taken from enemy champions for 25 seconds.Shadow Mending: Grants 9 Health Regen per 5 for up to 10 seconds after taking damage from an enemy champion or when the Spell Shield breaks.RecipeHexdrinker1,350g (550g to combine)Attack Damage25Magic Resist25Lifeline: Upon taking magic damage that would reduce Health below 30%, grants a Shield that absorbs 250 magic damage for 5 seconds (90 second cooldown).RecipeMercury's Treads1,200g (475g to combine)Magic Resist25Enhanced Movement: 45 Move SpeedTenacity: Reduces the duration of Stuns, Slows, Taunts, Fears, Silences, Blinds, and Immobilizes by 35%.Recipe

Do not take the duel inside a prepared turret nest. Clear from max range when grenade is down, then look for a Condemn angle as he retreats; if grenade is available, keep Tumble to dodge it rather than to trade.

Later Vayne wins open side-lane chases, but Heimer stalls areas and makes teamfight entrances awkward. Force him to move first, then fight away from turrets instead of proving you can drain-tank them.

• •If rockets are targeting the closest enemy, minion positioning matters before you step up.
• •A blinded Vayne loses Silver Bolts pressure; back off until it ends.
• •Condemn can push him out of turret protection if he walks forward to grenade.

BuyMercury's Treads1,200g (475g to combine)Magic Resist25Enhanced Movement: 45 Move SpeedTenacity: Reduces the duration of Stuns, Slows, Taunts, Fears, Silences, Blinds, and Immobilizes by 35%.RecipeBanshee's Veil2,750g (875g to combine)Health450Magic Resist55Intangibility: Grants a Spell Shield that blocks the next enemy ability. This Shield refreshes after no damage is taken from enemy champions for 25 seconds.Shadow Mending: Grants 9 Health Regen per 5 for up to 10 seconds after taking damage from an enemy champion or when the Spell Shield breaks.Recipe

Stay at auto range and chip the shield rather than blowing Condemn into it. Bait Howling Gale or Zephyr first, then use Final Hour after Monsoon or when she is too close to disengage cleanly.

Later Vayne wins side lane if Janna is isolated and Monsoon is down, but Janna is much better in teamfights because she peels your dive. Attack the frontline and save Tumble invisibility to dodge tornado or re-enter after Monsoon.

• •Do not Condemn into Eye of the Storm unless it pins her to a wall.
• •Her 475 attack range lets you punish autos without entering tornado charge range for long.
• •If Monsoon pushes you away, stop chasing until Night Hunter can re-engage safely.

BuyBoots of Swiftness1,000g (675g to combine)Enhanced Movement: 60 Move SpeedSlow Resist: Movement slowing effects are reduced by 25%.Recipe

Hold max range and never line up with Demacian Standard plus Dragon Strike. If he misses the knockup, punish hard; if he ults, Condemn him away inside the arena and use Final Hour Tumble to buy time until the wall drops.

Later Vayne can shred Jarvan in side lane if his combo is down, but he remains a high-value teamfight engager. Stay behind terrain or allies until Cataclysm is used, then clean up with Silver Bolts.

• •Tumble perpendicular to the flag line, not backward along it.
• •Martial Cadence hurts most on his first hit; avoid giving him a free opener.
• •Condemn does not remove Cataclysm, but it can create enough space inside it.

BuyNinja Tabi1,000g (375g to combine)Armor25Ninja Footwork: Blocks 10% of the damage from Basic Attacks.Enhanced Movement: 45 Move SpeedRecipeGuardian Angel2,750g (1,310g to combine)Armor50Magic Resist40Guardian's Intervention: Upon taking lethal damage, restores 30% of maximum Health and Mana after 4 seconds of stasis (5 minute cooldown).RecipeQuicksilver Sash1,550g (830g to combine)Magic Resist45Active: 90s Removes all debuffs.Recipe

Do not trade into Counter Strike; Tumble away and save Condemn for the end of the dodge or the Leap Strike follow-up. Commit only after Counter Strike is down, then kite at max range and use Final Hour invisibility to break his target timing.

Later Finished Jax usually wins extended side-lane duels if he reaches you, while Vayne is stronger at killing tanks in structured teamfights. Keep side waves short, ward flanks, and force him to spend Leap before you use Condemn.

• •Counting Counter Strike matters more than counting his health bar.
• •Condemn after he lands or as Counter Strike ends; firing during dodge wastes the fight.
• •Final Hour Tumble can make him mistime the stun radius.

BuyNinja Tabi1,000g (375g to combine)Armor25Ninja Footwork: Blocks 10% of the damage from Basic Attacks.Enhanced Movement: 45 Move SpeedRecipeGuardian Angel2,750g (1,310g to combine)Armor50Magic Resist40Guardian's Intervention: Upon taking lethal damage, restores 30% of maximum Health and Mana after 4 seconds of stasis (5 minute cooldown).RecipeQuicksilver Sash1,550g (830g to combine)Magic Resist45Active: 90s Removes all debuffs.Recipe

Fight at the edge of auto range and Tumble sideways after every attack rhythm instead of running in straight lines. If Wall of Pain is missed or crossed late, turn on him; after he dies, leave Death Defied range immediately and respect Requiem cleanup.

Later Vayne wins the side-lane duel if she avoids Wall, but Karthus often has more teamfight value through Defile, passive casting, and Requiem. Build a spell shield or revive effect if his global damage is deciding close fights.

• •Do not stand still for isolated Lay Waste; that is his best damage pattern.
• •Condemn him out of Defile if he walks at you after Wall.
• •After killing him, stop autoing and walk out before spending lifesteal time in passive.

BuyBanshee's Veil2,750g (875g to combine)Health450Magic Resist55Intangibility: Grants a Spell Shield that blocks the next enemy ability. This Shield refreshes after no damage is taken from enemy champions for 25 seconds.Shadow Mending: Grants 9 Health Regen per 5 for up to 10 seconds after taking damage from an enemy champion or when the Spell Shield breaks.RecipeGuardian Angel2,750g (1,310g to combine)Armor50Magic Resist40Guardian's Intervention: Upon taking lethal damage, restores 30% of maximum Health and Mana after 4 seconds of stasis (5 minute cooldown).RecipeHexdrinker1,350g (550g to combine)Attack Damage25Magic Resist25Lifeline: Upon taking magic damage that would reduce Health below 30%, grants a Shield that absorbs 250 magic damage for 5 seconds (90 second cooldown).Recipe

Keep enough distance that Riftwalk alone does not put him behind you. If he spends Null Sphere early, you can Final Hour and chase; if he holds silence, wait it out with movement before using Condemn to stop the second Riftwalk sequence.

Later Kassadin becomes harder to pin down in side lane once Riftwalk is low cooldown, while Vayne is stronger in front-to-back teamfights if he cannot reach her. Keep vision deep and do not isolate yourself where he can stack Riftwalk damage before the duel starts.

• •His passive does little against your physical and true damage; the problem is access, not durability.
• •Do not Tumble aggressively while Null Sphere is ready.
• •A spell shield blocking Null Sphere can turn the duel completely.

BuyBanshee's Veil2,750g (875g to combine)Health450Magic Resist55Intangibility: Grants a Spell Shield that blocks the next enemy ability. This Shield refreshes after no damage is taken from enemy champions for 25 seconds.Shadow Mending: Grants 9 Health Regen per 5 for up to 10 seconds after taking damage from an enemy champion or when the Spell Shield breaks.RecipeQuicksilver Sash1,550g (830g to combine)Magic Resist45Active: 90s Removes all debuffs.RecipeHexdrinker1,350g (550g to combine)Attack Damage25Magic Resist25Lifeline: Upon taking magic damage that would reduce Health below 30%, grants a Shield that absorbs 250 magic damage for 5 seconds (90 second cooldown).Recipe